muscular dystrophy

Sparing of the extraocular muscles in mdx mice with absent or reduced utrophin expression: A life span analysis

Sparing of the extraocular muscles in muscular dystrophy is controversial. To address the potential role of utrophin in this sparing, mdx:utrophin+/− and mdx:utrophin−/− mice were
examined for changes in myofiber size, central nucleation, and Pax7-positive and MyoD-positive cell density at intervals over their life span.