Blood Vessel Stenosis

Imaging via H&E Histology

While the histology can be measured live on a microscope, it is easier to stitch an image from several high resolution photos or take one photo at low resolution.

H&E Histology

The EEL is Defined and Edited

Using BIOQUANTs Editing Tools, the histologist defines the EEL boundaries. Once defined, BIOQUANT will use the defined threshold to automatically measure the EEL and IEL.

Measure the EEL

Once defined, Measure the EEL.

The External Elastic Lamina is Measured

Using the Existing Threshold, Limit to the IEL

Measure the IEL

Measure the IEL based on the modified threshold.

The Internal Elastic Lamina is Measured

Threshold and Limit the Lumen Area

The lumen has enough contract from surrounding tissue to be automatically measured. Threshold the Lumen, then, using BIOQUANTs Editing Tools, Keep the Lumen.

Measure the Lumen

BIOQUANT will automatically collect the Lumen data and perform calculations using the updated information.

Lumen Data has been Measured and Collected. Stenosis % has been calculated.

Stenosis and Stent Performance

Once the primary data are collected, the software internally processes the data to produce a final report. 

Images with or without schematic markup are saved to compliment the quantitative data.

Computed Data

  • Stent to Lumen Distance

  • External Elastic Lamina Area

  • Internal Elastic Lamina Area

  • Lumen Area

  • Medial Area

  • Intimal Area

  • % Stenosis

  • Total Stent Area

  • Total Scar Area